combination of two blood-pressure lowering medicines: Bisoprolol and Hydrochlorothiazide. Bisoprolol is a beta blocker which works specifically on the heart to reduce heart rate and make the heart more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow

Nausea
Constipation
Fatigue
Headache
Diarrhea
Dizziness
Cold extremities
Slow heart rate
Increased blood uric acid
Decreased potassium level in blood
Glucose intolerance
Altered blood lipids
Decreased magnesium level in blood
Increased calcium level in blood